The Terri Schiavo case was a huge start of the Right to Die movement, the underlying cause of Schiavos collapse was never given a diagnosis. Retrieved April 13, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110695/, Blakemore, E. (2017). Bioethics in relation to savior siblings is fundamental in explicating the dynamics of the physician, the child, and the parents. as the guardian and caretaker the mother must decide what would be the best option for the patient, but denial would be unethical as it conflicts with Article 1. Further, it could help demonstrate what to do next in a growing technological climate. Would you like email updates of new search results? A savior sibling is a child who is born to be genetically compatible with a sibling that is suffering from a life-threatening disease. This is why they leave regulation to the states and private sector (McClean, 851). describes a scenario where human cloning is not only affordable but encouraged; although the clones are not perceived as people by the general public, they are seen as extra organs since they are confined. The saviour sibling will always feel less loved. When there is a lack of law, there is theory to be applied. <]/Prev 321019>> Epub 2022 Sep 9. It would be incredibly hard to make this life or death decision on another human being and twice as hard when it is someone we love. Through the use of in-vitro fertilization (, Various ethical frameworks and their relation to savior siblings ethics topics, Focus on various power differentials and vulnerable groups, Focus on the future bodily well-being of everyone in the society, Medical advancements allow for development of healthier society. Take a second to imagine that your child is born with a life-threatening heritable disease. This is an example of a savior sibling, a child who is born to provide an organ or cell to a sibling that is suffering from a life-threatening disease. Retrieved April 06, 2017, from http://content.time.com/time/magazine/article/0,9171,138483,00.html, Read Scientific and Medical Aspects of Human Reproductive Cloning at NAP.edu. Infographic made by Travis Hooven using Canva. So, from the perspective of a consequentialist an ethically right act is the one that will inherit good outcome or consequence. (1) Parents must be informed of all risks and benefits encompassed in transplant procedure, (2) Parents who take care of the child must be able to provide adequate emotional support, (3) There must be a close, existing relationship between the donor sibling and the recipient sibling, : this process removes the chromosomes from an egg and replaces it with the nucleus from a somatic cell, this includes skin or blood. Because of the skill and knowledge the doctor has over the patient, the patientsinterests must be involved when a physician provides medical advice. Situations where medical help is essential, itbecomes complicated when considering consent and the capacity of the patient. Adoption is technically defined as a two-step judicial process in conformance to state statutory provisions in which the legal obligations and rights of a child toward the biological parents are terminated and new rights and obligations are created in the acquired parents (Adoption 1). Federal government websites often end in .gov or .mil. Plenty of studies show that savoir siblings grow. FOIA Of the embryos that are tested and matched one of them is implanted into the mothers womb for the embryo to grow and develop (PGD, September 02 2016). A savior sibling can be defined as a baby born in order to help save their sibling by the use of compatible parts. Sadly the experiment resulted with five pregnancies out of sixty-seven embryos. The creation of savior siblings has been the subject of intense ethical debate over the past decade. In this case greatest happiness would be the potentiality of ridding genetic diseases in a living child. Therefore, it is meant to give birth to a child who will provide stem-cells taken from the umbilical cord or bone marrow afterwards, to treat an elder sick sibling. Unable to load your collection due to an error, Unable to load your delegates due to an error. Rahal I, Galambrun C, Bertrand Y. In the case of a savior sibling, the parents are acting unethically by having a child for the purpose of saving the life of a second child and not for the sake of the child being born. Feminist bioethics also helps analyze the power differential between patient and practitioner, where the patients are the parents of the savior sibling (Zierhut, 2013). For example, some people think health care should be a human right as others think it should only be available to those who can pay for it. Retrieved April 13, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563311/, SPARMAN, M. L., Tachibana, M., & MITALIPOV, S. M. (2010). eCollection 2021 Jun. Haematologica. Throughout history many great philosophers have attempted to unravel the origins of virtues by developing moral theories of their own. Parfits strongest argument towards his claims is that there is no continual existence of the definite ego or personal identity. Retrieved April 18, 2017, from https://www.youtube.com/watch?v=fWPh3vJdl24, My Sisters Keeper. Ethics can be explained as principles a society develops to guide decisions about what is right and wrong. This document is designed to provide the reader with an overview of some of the more popular theories concerning morals. The mosaic effect is where epigenetic defects are expressed differently and unevenly throughout an organism. endobj A savioursibling could be treated as a person as well as someone who can bring healing to another. Feminist bioethics, flourishing societies and human rights perspectives are three frameworks that effectively allow us to delve deeper and further explore these ethical problems associated with savior siblings. Retrieved April 15, 2017, from http://www.sparknotes.com/lit/my-sisters-keeper/summary.html, Preimplantation Genetic Diagnosis: Benefits & Concerns. In this case greatest happiness would be the potentiality of ridding genetic diseases in a living child. At the age of 5, Picoults sonwas diagnosed with cholesteatoma which resulted in numerous surgeries due to the tumors in his ears. It is difficult for this technology to be shared equally and free from discrimination due to the availability of the technology (price, location, etc.) Elective non-therapeutic intensive care and the four principles of medical ethics. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). the parents should not be allowed to decide this because they have a conflict of interest towards the sick child. Conception of Saviour Siblings: Ethical Perceptions of Selected Stakeholders in Malaysia. The development of savior siblings became one of the most influential technologies in the field of obstetrics, embryology, and genetics. official website and that any information you provide is encrypted Childrens Anatomy v. Childrens Autonomy: Precarious Balancing Act with Preimplantation Genetic Diagnosis and the Creation of Savior Siblings. Careers. Observing savior siblings in an ethical framework, specifically Bioethics, could help others better understand what is at stake and what the moral implications are. When their autonomy is not seen legally? ^#.LbG\AR61]>={3kdcAG_;'oo> &5d P4"pW 7bK'@L&ruHHbOd|NsSjwt&;P'hWN0u3u*#dS[ED"\N[^=({*x^8Rr>*jQDM\5N;CnrSMYQblg5c+[P)7wp>8ufW3m`0A@Y#Pg$=5/hyG[w kn. All children should be valued for being children of God, not for what they can do for another. Prenat Diagn. Molly showed improvement in 4 weeks, and in three years her immune system was normal. Through trial and error scientists were able to inject the pig embryos with human stem cells that did not die after a few weeks of gestation in adult pigs (Blakemore, 2017). Retrieved April 18, 2017, from https://www.nature.com/scitable/forums/genetics-generation/case-study-in-savior-siblings-104229158, Garcia-Santillan, A. D. (n.d.). However, for stem cells to thrive and differentiate into other cell types they must be in the proper environment to do so. Purpose of the study: To discuss the ethical challenges for the therapeutic team when dealing with a young savior sibling as a potential tissue donor. Iowa House File 233 has passed its first legislative committee. 2005 Oct;33(10):833-4. doi: 10.1016/j.gyobfe.2005.07.037. Many human rights ethicists are divided on this issue, because some view embryos as human while other dont. attaining greatest happiness. 0000022783 00000 n To set up a discussion on the ethical issues My Sister's Keeper raises I showed selected scenes from the 2009 film (directed by Nick . Once the sibling is born their umbilical cord blood can be used as a source of healthy, new bone marrow for the sick child. - Cases & Ethics, What Are Savior Siblings & How Are They Created? The story follows a young girl named Anna suing her parents for medical emancipation. 2019;54:1121-1123. Our methodological basis is the principlism approach by Beauchamp and Childress, consisting of four principles: autonomy, non-maleficence, beneficence, and justice. Although this may be true in some cases it is not in all so explaining the wrongness of killing, between the common debates whether a fetus does or does not obtain human hood, should be illustrated in a way of a virtuous theory. Retrieved February 27, 2017, from https://docs.google.com/document/d/1KTpM0GThCfSaaPPgOjrkjxjFoSlBQT72ibExMLDOhZ8. 0000000796 00000 n There is also a clear value of life for the savior sibling when the act denies right to organ donation. And are savior siblings, at all, ethical? Each branch of Philosophy has their own view and opinions, that, Consequentialist believe that morality is about producing the right overall consequences, and that the action brings about either happiness, freedom or survival of species. Retrieved April 13, 2017, from, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563311/, SPARMAN, M. L., Tachibana, M., & MITALIPOV, S. M. (2010). <<>> Analytical cookies are used to understand how visitors interact with the website. We used a case including a 19-year-old thalassemia patient and his two and a half year old sister from our practice as ethics consultants. At first glance, one would consider the desires of the Ayala family heroic, but however, each decision incorporates various moral issues which must be considered. Zierhut, H., MacMillan, M.L., Wagner, J.E. We already do this with pig farms; raising pigs to kill them for food, These human-pig embryos would be used to save humans. (n.d.). We use our own and third party cookies that provide us with statistical data and your browsing habits; with this we improve our content, we can even show advertising related to your preferences. The equal moral status framework states that all human beings are of equal status, regardless of their race, age, size, or even developmental stage (Harvard Magazine, 2009). This article will provide a brief background on the history of savior siblings within the United States and how it has been portrayed in the media. HIV/Drug Abuse Prevention Research Ethics Training Institute. This lack of regulation could gravely affect the future of savior children and how they are treated. Pigs were a great candidate because of their similarities to humans. It does not store any personal data. 8600 Rockville Pike If these embryos are considered human, then their fundamental rights are being violated. Some theories that can be used include utilitarianism, Kants ethics and natural law theory. 2. The author discusses the argument of this controversial topic of sustaining life at any cost or dying peacefully as an ethical issue. Thus the ethical choice by rights is to undergo HRC. UhXmfxYMlA:9FVJFs9z,Z.<3foR0.-VC o4MYA&!oNrrL?{}DaMGY5DCj+gl,'}t c!PCW\kE'iPBI9Vg[u1X9Ba]:^`rh\w{92*Qx:K_,g^m-g/Ze,b9n\ R?tD]k[W\Iu6A} @:8wZ0aQ What happens when children are not able to make decisions for themselves? (n.d.). PMC It also required the Center for DiseaseControl to develop a model for these clinics to follow in order to obtain certification for embryo laboratories. Does the savior sibling want to be created for the purpose of another life? This novel is based on a family faced with the idea of creating a savior sibling Many savior siblings tend to be psychologically effected from being a donor sibling, they are effected by knowing that if their sibling didnt need a donor match they would not exist, many savior siblings lack the attention they need because they are a secondary thought to their older ill sibling. Retrieved April 01, 2017, from https://www.nap.edu/read/10285/chapter/4#26, Elsner, D. (2006, October). My oldest brother was adopted, in addition to eight of my cousins, and I am so thankful that each one of them had the opportunity to be placed in my family. Feminist bioethics also challenges the binary view of humanity, in that they argue that there is no cut-off date for a being to be deemed human, or not human. Rather, feminist bioethics acknowledges that different developmental stages incite different magnitudes of humanity, and that as the embryo further develops it gradually acquires more humanity.. Copyright Get Revising 2023 all rights reserved. While a great number of associations fight agains fatal diseases like beta thalassemia or Fanconi anemia are in favor of savior siblings, the Catholic church and pro-life groups are against allowing parents to use savior siblings. This site needs JavaScript to work properly. Just another reproductive technology? In conclusion, the pros and cons of saviour siblings are complex and multifaceted. 2018 Sep 30;49(3):228-235. doi: 10.25100/cm.v49i2.3619. Argues that savior siblings are unethical because they are not given the choice for organ donation. An official website of the United States government. In Divided Minds and the Nature of Persons, Derek Parfit purposes that we as humans should separate what we consider identity and survival. This site needs JavaScript to work properly. <> Allows SESSION variables to be stored on the web server. Table 1. https://doi.org/10.3324/haematol.2018.213207, NCI CPTC Antibody Characterization Program. endobj However, for stem cells to thrive and differentiate into other cell types they must be in the proper environment to do so. New Prospects for Growing Human Replacement Organs in Animals The New York Times. These defects are next to impossible to detect due to the mosaic effect in developing embryos. Because children with the same parentshave a one and four chance of sharing the same Human Leukocyte Antigen (HLA) genes, sometimes the only means to save a child from a terminal disease is through a savior sibling. The use of these technologies allow for medical advancements, which would be supported by flourishing societies framework, as the main focus is on the bodily well-being of everyone in the society. The United Kingdom is a perfect place to look. Join us on Sundays at 8am and 11am. As commissioner of DPCD, Mr. Walker provides leadership and policy direction for the Offices of Planning, Buildings, and Housing. Definitely a great topic . A fictional savior sibling is one of the main characters in Jodi Picoult's popular novel, My Sister's Keeper (2005), in which parents have a child to serve at first as a bone-marrow donor and later as an organ donor for their dying first child. Consider potential future familial ties between savior sibling and family, Consider the existing relationship between the donor sibling and the recipient sibling. Imf pros and cons. Accessibility When Adam was born a stem cell transplantation was done immediately and infused into his sister Mollys circulatory system. Ethics in health care play a vital role every day. To discuss the ethical challenges for the therapeutic team when dealing with a young savior sibling as a potential tissue donor. Adam Nash was the first baby in the United States to be born throughsavior sibling technology to save his older sister Molly who was suffering from Fanconi anemia. What does the best interests principle of the convention on the rights of the child mean for paediatric healthcare? Naturally, there is no concrete answer to the ethical dilemma behind savior siblings. This is just another good reason to have a child. Bethesda, MD 20894, Web Policies 2017 Nov 9;18(1):61. doi: 10.1186/s12910-017-0219-4. Registered office: International House, Queens Road, Brighton, BN1 3XE, arguments for and against saviour siblings. Traditional medicinal treatments such as drugs andother sorts of medication are not adequate to rectify the disorder and there is only one treatment for this condition, a bone marrow transplant. Determined three critical factors for a transplant to be in best interest of donor child (McClean, 856-857). Figure 2: An example of the differing states legal ruling on the topics of pre-implantation genetic diagnostics and in-vitro fertilization. McClean, M. (2016). 439 0 obj Kennedy Inst Ethics J. 12/02/2021 No Comments. 0000018256 00000 n Because the government of the United Kingdom has consistently been concerned and involved with the medical field, there is more regulation and organization behind some of these technologies. Elizabeth Andersen is a current candidate in theEthics and Society Masters programat Fordham University. In France, this practice, authorized by the Bioethics Law of August 2004 and confirmed by its decree of implementation published in the Official Journal on 23 December 2006, is also strictly regulated. saving the life of your sibling. [Preimplantatory genetic diagnosis and saviour sibling: ethical criteria found in the biomedical and bioethics literature]. Cloning of non-human primates: the road less traveled by. 0000001527 00000 n There are four basic principles to Bioethics: (1) respect for autonomy, (2) beneficence, (3) non-maleficence, and (4) justice. He supports some of his beliefs by contrasting Egos Theory to the Bundle Theory, a theory suggesting that our minds are a collection of none cohesive properties, related only by our consciousness and resemblance, with the studies of imaginary patients who may suffer from disorders known as split-brain cases. As soon as Adam was born, his umbilical cord was used as a bone marrow transplant for his sister. Principal conclusions: Basic procedures: Savior siblings are children that are created to serve a sibling as a donor of umbilical cord blood, bone marrow, or peripheral blood from which hematopoietic stem cells are. We found that the main conflict arises between the autonomy of the savior sibling as well as the non-maleficence regarding her and the beneficence of the thalassemia patient. This technology requires for embryos to be created in vitro from the mother's egg and father's sperm. A common scenario that addresses the power differential between an embryo and human is the who would you save if both a baby and petri dish holding an embryo were in danger, often prompting people to save the baby. A savior sibling refers to the creation of a genetically matched human being to provide biologically materials such as blood, bone marrow or even organs to a fatally ill sibling. government site. Some of the basic questions argued that may perhaps characterize the importance of the issue: Is abortion morally justifiable? Bone Marrow Transplant. Utilitarianism is an example of consequentialism that maximizes utility (happiness). <>/Border[0 0 0]/Rect[243.264 211.794 465.084 223.806]/Subtype/Link/Type/Annot>> Saviour siblings could also live for both. However, there is no guarantee of success if parents elect to move forward with this option. What Are Savior Siblings & How Are They Created? Even if the sibling giving the organ suffers, suffering is a fact of life so it shouldn't matter - 'Dukkha'. Originally named medicine babies, savior babies have been a more recent discovery in the medical world, presenting families with a quick fix to dealing with terminally ill children. New Prospects for Growing Human Replacement Organs in Animals The New York Times. 0000010385 00000 n If a doctor promises to do no harm, who is he promising- the child or the parents and to what extent? The major ethical arguments for and against the use of preimplantation genetic diagnosis (PGD) for human leukocyte antigen (HLA) tissue typing are analysed. To keep all these cookies active, click the Accept button. Case Study in Savior Siblings. does not include potential psychological disorders that may manifest. As of 2004 SCNT had 1% to 4% chance of success for live birth and few primates had successfully be cloned. Disclaimer. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Currently, state regulation of PGD and savior siblings is sufficient because the technology has yet to be widely used. <> 0000002467 00000 n This raises concern for the welfare of the child being created. This cookie is set by GDPR Cookie Consent plugin. Its legalisation is certainly justified by the suffering of the parents and to avoid that they travel to other States where it is permitted. 1. 2022 Nov;181(11):3805-3816. doi: 10.1007/s00431-022-04609-2. H3)AV8@6Ael@z;2/ -`1A i {?dN0U`%AA!!g"v.&hR "71f0^ y33C Rz Hs\X*g`33[X1 3H BMC Med Ethics. Further, I will rationalize the ethical dimensions and questions that could stem from the morality of savior siblings and the possibility of potential abuse. These are just some of the questions that are brought to light when analyzing savior siblings in a Bioethics framework. How sick is the child and if he or she gets treatment from a savior sibling, will it benefit in the end? The debate whether abortion is morally permissible or not permissible is commonly discussed between the considerations of the status of a fetus and ones virtue theory. For humans, it seems impossible to determine whether altering life is truly the right thing to do. HHS Vulnerability Disclosure, Help Following an analysis of the English and French laws on saviour siblings, its controversial side will be highlighted, before concluding whether or not this new Pandora's box which is saviour-sibling, should be closed and other alternative methods encouraged. Basic procedures: Retrieved April 18, 2017, from, https://www.nature.com/scitable/forums/genetics-generation/case-study-in-savior-siblings-104229158, Garcia-Santillan, A. D. (n.d.). 0000000016 00000 n The child is born to provide either organ or cell transplant, and/or blood transfusions for the ill sibling. The site is secure. The growth process for clones is different from natural birth (home environment, memories) thus making it impossible for clones (lab environment,different memories, aged genetic material) to be exactly the same though they will be genetically similar. Bethesda, MD 20894, Web Policies Due to this reasoning, ethicists following this framework view this technology as unethical. The most optimal outcome would be if the mother has the AC and, if she is unable to to care for a second child, an adoption program could be instigated like the form of the 2007 movie. World Human Cloning Policies. Should and can the mother provide for two children? sharing sensitive information, make sure youre on a federal Disclaimer. The therapeutic team does not only have to recognize the principal vulnerability of children but also the different scales of vulnerability depending on their age. Having another child that will match the HLA type of the patient. [Preimplantation genetic diagnosis in order to choose a saviour sibling]. A fiduciary duty is a legal responsibility between at least two parties (a doctor and a patient). Retrieved April 17, 2017, from http://americanpregnancy.org/infertility/preimplantation-genetic-diagnosis/, Rivard, L. (n.d.). Part of this practice involves taking multiple eggs and sperm and fertilizing them. Advanced Certificate in Health Care Ethics, help save their sibling by the use of compatible parts, understood they came second to his well-being, 1992 Fertility Clinic Success Rate and Certification Act (FCSRCA), There are four basic principles to Bioethics, to enable the identification of a tissue match for an older sibling suffering from a life-threatening illness, where umbilical cord blood is to be used in treatment., Fordham University HIV and Drug Abuse Prevention Research Ethics Training Institute, RELAY Research Equality for LGBT+ and Allied Youth. inviTRA Copyright 2023 by Eureka Fertility. Each of these principles has equal importance and complexity when dealing with ethical decision making. I will explore law, or lack thereof, surrounding savior siblings and how this can affect future complications when it comes to the procedures that create savior siblings. The procedures can be painful and even life-threatening. Unlike a Kantian, a utilitarian would do as much as they can to bring about pleasure, even if it meant putting the second child in danger/pain to save the first childs life. Depending on what one may consider as life, this could be a heinous act committed. She believed she gave too much of her to her sister such as; blood transfusions, bone marrow and a kidney (My Sisters Keeper). A savior sibling can be defined as a baby born in order to help save their sibling by the use of compatible parts. In the United Kingdom, it is required that a clinic is licensed in order to perform the savior sibling procedure. ku qj vj. A nine year old girl from Norfolk has had a life-saving transplant from a so-called saviour sibling. Of Headless MiceAnd Men. An ethicist, a person who specializes in or writes on ethics, can provide valuable discernment with respect to right and wrong motives or actions. Retrieved April 13, 2017, from, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110695/, Wade, N. (2017). hi. Get Revising is one of the trading names of The Student Room Group Ltd. Register Number: 04666380 (England and Wales), VAT No. When Anna realizes having only one kidney translates to a predetermined future for herself, she tells her parents that she does not want to give Kate her kidney, ultimately tearing the family apart. This altered egg is then implanted to the uterus of an animal, if the implant is successful the result will be an animal clone through natural birth. It is important to carefully consider all of these factors before deciding to pursue the creation of a saviour sibling. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). pd. Main findings: Pregnant mothers do not exist just for themselves but for the unborn babies as well. and transmitted securely. endobj Fertility treatments for couples: how to achieve pregnancy? In parallel, the scientific body has never since ceased to debate the ethical issues that they arise. 2021 Mar 17;13(2):167-178. doi: 10.1007/s41649-021-00166-2. 2013;118:1-9. doi: 10.1016/B978-0-444-53501-6.00001-9. Being aware of the case already, I believe there should be some sort of law that gives doctors to comply with the wishes of the patient if they are in a lot of distress. He was brought into the world for the forgiveness of all our sins. 2004;14(1):81-96. 0000002724 00000 n I will analyze the moral foundation of Bioethics to help comprehend the complexity of the issue of savior siblings. Scientists needed to introduce human stem cells, cells that have the potential to become different types of tissue, to a pig embryo in order to create a human-pig embryo hybrid (Wade, 2017). MeSH My argument will based on the following ethical principles and theories: Utilitarianism, Respect for Autonomy and Virtue. (2009, March 30). 2002 Oct;28(5):289. doi: 10.1136/jme.28.5.289. Analyzing other countries laws could benefit the United States in determining how something such as savior siblings should be managed. This is particularly the case regarding saviour-sibling. Before January 26, 2017 the ability to produce a human-animal hybrid had yet to be done (Blakemore, 2017). These cookies ensure basic functionalities and security features of the website, anonymously. 438 25 Human flourishing, the capacity to attain self-actualization and fulfillment in society, and human dignity, the inherent rights to be valued and treated ethically, propel each moral issue into consideration. Copyright Get Revising 2023 all rights reserved. Video created by Jessica Cornell using PowToon. While this novel is fiction, Jodi Picoult has talked about the ways in which she came to research this topic of savior siblings and how it relates to her own life. endobj In 1990, they established a Human Fertilization and Embryology Act which allows for testing and tissue matching for savior siblings but under very strict criteria. Do we want to live in a society where it is ethical to raise pigs only to kill them? Since the advent of test-tube babies, advances in the biomedical field have risen steadily. xXnFSh_$X_S>@PoZA8i}9GPZ Those phrases are the reason that the strong version is an ideal view instead of a realistic. savior siblings ethics pros and cons. The researchers are extremely confident that they would be capable of doing a similar procedure on a human, thus creating an unconscious, brainless human body that could not be considered a person and so it should be perfectly legal to store them as a future source of organs (Krauthammer, 2001). <>/Border[0 0 0]/Rect[480.18 617.094 549.0 629.106]/Subtype/Link/Type/Annot>> It usually explains the saying the end justifies the means which means that in order to achieve a goal, take any route which leads to achieving it. It's the. One such philosophical issue is the moral permissibility of infanticide. savior sibling is one of ethical issue that has been run for a long time, savior sibling refer to the child who creates by an artificial method using of vitro preparation (IVF) and Preimplantation genetic diagnosis (PGD).

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